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1

Membrane lipid therapy: Modulation of the cell membrane composition and structure as a molecular base for drug discovery and new disease treatment

Escribá, Pablo V., Busquets, Xavier, Inokuchi, Jin-ichi, Balogh, Gábor, Török, Zsolt, Horváth, Ibolya, Harwood, John L., Vígh, László

Journal:

Progress in Lipid Research

Year:

2015

Language:

english

File:

PDF, 2.01 MB

english, 2015

2

[Progress in Molecular Biology and Translational Science] Gangliosides in Health and Disease Volume 156 || Biology of GM3 Ganglioside

Inokuchi, Jin-ichi

Year:

2018

Language:

english

File:

PDF, 1.66 MB

english, 2018

3

Overexpression of HexCer and LacCer containing 2-hydroxylated fatty acids in cholangiocarcinoma and the association of the increase of LacCer (d18:1-h23:0) with shorter survival of the patients

Silsirivanit, Atit, Phoomak, Chatchai, Teeravirote, Karuntarat, Wattanavises, Sasiprapa, Seubwai, Wunchana, Saengboonmee, Charupong, Zhan, Zhaoqi, Inokuchi, Jin-ichi, Suzuki, Akemi, Wongkham, Sopit

Journal:

Glycoconjugate Journal

Year:

2019

Language:

english

File:

PDF, 1.02 MB

english, 2019

4

Effects of D-threo-PDMP, an inhibitor of glucosylceramide synthetase, on expression of cell surface glycolipid antigen and binding to adhesive proteins by B16 melanoma cells

Jin-Ichi Inokuchi, Keiko Momosaki, Hiroshi Shimeno, Atsuo Nagamatsu, Norman S. Radin

Journal:

Journal of Cellular Physiology

Year:

1989

Language:

english

File:

PDF, 1.31 MB

english, 1989

5

Pseudosugars, 35. Synthesis of glycosylceramide analogs composed of imino-linked unsaturated 5a-carbaglycosyl residues: Potent and specific gluco- and galactocerebrosidase inhibitors

Hidetoshi Tsunoda, Jin-Ichi Inokuchi, Kiwamu Yamagishi, Seiichiro Ogawa

Journal:

European Journal of Organic Chemistry

Year:

1995

Language:

english

File:

PDF, 673 KB

english, 1995

6

Synthesis of potent β-D-glucocerebrosidase inhibitors: N-alkyl-β-valienamines

Seiichiro Ogawa, Makoto Ashiura, Chikara Uchida, Shinsuke Watanabe, Chihiro Yamazaki, Kiwamu Yamagishi, Jin-ichi Inokuchi

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1996

Language:

english

File:

PDF, 193 KB

english, 1996

7

Physiological levels of insulin and IGF-1 synergistically enhance the differentiation of mesenteric adipocytes.

Takashige Sato, Masakazu Nagafuku, Kyoko Shimizu, Toshio Taira, Yasuyuki Igarashi, Jin-ichi Inokuchi

Journal:

Cell Biology International

Year:

2008

Language:

english

File:

PDF, 486 KB

english, 2008

8

Involvement of membrane microdomains in the pathogenesis of metabolic syndrome and asthma

Jin-ichi Inokuchi

Journal:

Chemistry and Physics of Lipids

Year:

2011

Language:

english

File:

PDF, 204 KB

english, 2011

9

Membrane microdomain malfunction and insulin resistance in type 2 diabetes

Jin-ichi Inokuchi

Journal:

Colloids and Surfaces A: Physicochemical and Engineering Aspects

Year:

2006

Language:

english

File:

PDF, 328 KB

english, 2006

10

Synthesis and biological evaluation of four stereoisomers of PDMP-analogue, N-(2-decylamino-3-hydroxy-3-phenylprop-1-yl)-β-valienamine, and related compounds

Seiichiro Ogawa, Tamami Mito, Eiichi Taiji, Masayuki Jimbo, Kiwamu Yamagishi, Jin-ichi Inokuchi

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1997

Language:

english

File:

PDF, 291 KB

english, 1997

11

Chemical modification of β-glucocerebrosidase inhibitor N-octyl-β-valienamine: synthesis and biological evaluation of N-alkanoyl and N-alkyl derivatives

Seiichiro Ogawa, Yuko Kobayashi, Kazuya Kabayama, Masayuki Jimbo, Jin-ichi Inokuchi

Journal:

Bioorganic & Medicinal Chemistry

Year:

1998

Language:

english

File:

PDF, 204 KB

english, 1998

12

Expression of the β-Galactoside α1,2-Fucosyltransferase Gene Suppresses Axonal Outgrowth of Neuro2a Neuroblastoma Cells

Seiji Hitoshi, Naoya Kojima, Susumu Kusunoki, Jin-ichi Inokuchi, Ichiro Kanazawa, Shuichi Tsuji

Journal:

Journal of Neurochemistry

Year:

1996

Language:

english

File:

PDF, 1.13 MB

english, 1996

13

Induction of Ganglioside Biosynthesis and Neurite Outgrowth of Primary Cultured Neurons by l-threo-1-Phenyl-2-Decanoylamino-3-Morpholino-1-Propanol

Seigou Usuki, Makoto Hamanoue, Shinichi Kohsaka, Jin-ichi Inokuchi

Journal:

Journal of Neurochemistry

Year:

1996

Language:

english

File:

PDF, 1.20 MB

english, 1996

14

Studies of the action of ceramide-like substances (d- andl-PDMP) on sphingolipid glycosyltransferases and purified lactosylceramide synthase

Subroto Chatterjee, Tavia Cleveland, Wan-Yang Shi, Jin-Ichi Inokuchi, Norman S. Radin

Journal:

Glycoconjugate Journal

Year:

1996

Language:

english

File:

PDF, 596 KB

english, 1996

15

Expression of ganglioside GM3 and H-2 antigens in clones with different metastatic and growth potentials isolated from Lewis lung carcinoma (3LL) cell line

Jin-ichi Inokuchi, Masayuki Jimbo, Yukihiro Kumamoto, Hiroshi Shimeno, Atsuo Nagamatsu

Journal:

Clinical and Experimental Metastasis

Year:

1993

Language:

english

File:

PDF, 865 KB

english, 1993

16

Triglyceride accumulation and altered composition of triglyceride-associated fatty acids in the skin of tenascin-X-deficient mice

Ken-ichi Matsumoto, Takashige Sato, Seiko Oka, Yasuko Orba, Hirofumi Sawa, Kazuya Kabayama, Jin-ichi Inokuchi, Hiroyoshi Ariga

Journal:

Year:

2004

Language:

english

File:

PDF, 293 KB

english, 2004

17

Glycoconjugates in the mammalian auditory system

Shinji Go, Misato Yoshikawa, Jin-ichi Inokuchi

Journal:

Journal of Neurochemistry

Year:

2011

Language:

english

File:

PDF, 679 KB

english, 2011

18

A Synthetic Ceramide Analog (l-PDMP) Up-regulates Neuronal Function

JIN-ICHI INOKUCHI, AKIHIRO MIZUTANI, MASAYUKI JIMBO, SEIGOU USUKI, KIWAMU YAMAGISHI, HIDEO MOCHIZUKI, KAZUYO MURAMOTO, KAZUO KOBAYASHI, YOICHIRO KURODA, KATSUNORI IWASAKI, YUSUKE OHGAMI, MICHIHIRO FUJ

Journal:

Annals of the New York Academy of Sciences

Year:

1998

File:

PDF, 446 KB

1998

19

GM2 Ganglioside Regulates the Function of Ciliary Neurotrophic Factor Receptor in Murine Immortalized Motor Neuron-Like Cells (NSC-34)

Seigou Usuki, Jin Ren, Iku Utsunomiya, Neil R. Cashman, Jin-ichi Inokuchi, Tadashi Miyatake

Journal:

Neurochemical Research

Year:

2001

Language:

english

File:

PDF, 2.37 MB

english, 2001

20

Glycosphingolipids govern gene expression

Jin-ichi Inokuchi, Kazuya Kabayama, Satoshi Uemura, Yasuyuki Igarashi

Journal:

Glycoconjugate Journal

Year:

2003

Language:

english

File:

PDF, 692 KB

english, 2003

21

Apoptosis of human carcinoma cells in the presence of inhibitors of glycosphingolipid biosynthesis: I. Treatment of Colo-205 and SKBR3 cells with isomers of PDMP and PPMP

Subhash Basu, Rui Ma, Brian Mikulla, Mathew Bradley, Christopher Moulton, Manju Basu, Sipra Banerjee, Jin-ichi Inokuchi

Journal:

Glycoconjugate Journal

Year:

2003

Language:

english

File:

PDF, 423 KB

english, 2003

22

The synthetic ceramide analog l-PDMP partially protects striatal dopamine levels but does not promote dopamine neuron survival in murine models of parkinsonism

J.S. Schneider, K.A. Bradbury, Yoshihiro Anada, Jin-ichi Inokuchi, D.W. Anderson

Journal:

Year:

2006

Language:

english

File:

PDF, 420 KB

english, 2006

23

Membrane microdomains and insulin resistance

Jin-ichi Inokuchi

Journal:

Year:

2010

Language:

english

File:

PDF, 1.05 MB

english, 2010

24

Dissociation of the insulin receptor from caveolae during TNFα-induced insulin resistance and its recovery by d-PDMP

Junji Sekimoto, Kazuya Kabayama, Kazutoshi Gohara, Jin-ichi Inokuchi

Journal:

Year:

2012

Language:

english

File:

PDF, 577 KB

english, 2012

25

A synthetic ceramide analog ameliorates spatial cognition deficit and stimulates biosynthesis of brain gangliosides in rats with cerebral ischemia

Kiwamu Yamagishi, Kenichi Mishima, Yusuke Ohgami, Katsunori Iwasaki, Masayuki Jimbo, Hiroyuki Masuda, Yasuyuki Igarashi, Jin-ichi Inokuchi, Michihiro Fujiwara

Journal:

European Journal of Pharmacology

Year:

2003

Language:

english

File:

PDF, 271 KB

english, 2003

26

Effects of Endoglycoceramidase ord-Threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol on Glucose Uptake, Glycolysis, and Mitochondrial Respiration in HL60 Cells

Li Ji, Makoto Ito, Gu Zhang, Yoshio Hirabayashi, Jin-ichi Inokuchi, Tatsuya Yamagata

Journal:

Archives of Biochemistry and Biophysics

Year:

1998

Language:

english

File:

PDF, 953 KB

english, 1998

27

Effects of Glucosylceramide Synthase Inhibitor and Ganglioside GQ1b on Synchronous Oscillations of Intracellular Ca2+in Cultured Cortical Neurons

Akihiro Mizutani, Yoichiro Kuroda, Kazuyo Muramoto, Kazuo Kobayashi, Kiwamu Yamagishi, Jin-ichi Inokuchi

Journal:

Biochemical and Biophysical Research Communications

Year:

1996

Language:

english

File:

PDF, 90 KB

english, 1996

28

Up-Regulation of Ganglioside Biosynthesis, Functional Synapse Formation, and Memory Retention by a Synthetic Ceramide Analog (l-PDMP)

Jin-ichi Inokuchi, Akihiro Mizutani, Masayuki Jimbo, Seigou Usuki, Kiwamu Yamagishi, Hideo Mochizuki, Kazuyo Muramoto, Kazuo Kobayashi, Yoichiro Kuroda, Katsunori Iwasaki, Yusuke Ohgami, Michihiro Fuj

Journal:

Biochemical and Biophysical Research Communications

Year:

1997

Language:

english

File:

PDF, 125 KB

english, 1997

29

Modulation of EGF Receptor Activity by Changes in the GM3 Content in a Human Epidermoid Carcinoma Cell Line, A431

Emmanuelle J. Meuillet, Barbara Mania-Farnell, David George, Jin-Ichi Inokuchi, Eric G. Bremer

Journal:

Experimental Cell Research

Year:

2000

Language:

english

File:

PDF, 370 KB

english, 2000

30

Rapid kidney changes resulting from glycosphingolipid depletion by treatment with a glucosyltransferase inhibitor

Girja S. Shukla, Arti Shukla, Jin-ichi Inokuchi, Norman S. Radin

Journal:

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism

Year:

1991

Language:

english

File:

PDF, 634 KB

english, 1991

31

Glucosphingolipids as sites of action in the chemotherapy of cancer

Norman S. Radin, Inokuchi Jin-Ichi

Journal:

Biochemical Pharmacology

Year:

1988

Language:

english

File:

PDF, 1.15 MB

english, 1988

32

Sphingosine inhibits attachment of murine Lewis lung carcinoma cells to laminin and type IV collagen

Jin-ichi Inokuchi, Yukihiro Kumamoto, Masayuki Jimbo, Hiroshi Shimeno, Atsuo Nagamatsu

Journal:

Year:

1991

Language:

english

File:

PDF, 632 KB

english, 1991

33

Glucosylceramide synthetase inhibitor, d-threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol exhibits a novel decarcinogenic activity against Shope carcinoma cells

Mamoru Kyogashima, Makoto Inoue, Akira Seto, Jin-ichi Inokuchi

Journal:

Year:

1996

Language:

english

File:

PDF, 3.77 MB

english, 1996

34

Specific expression of Neu2 type B in mouse thymus and the existence of a membrane-bound form in COS cells

Toshiaki Koda, Shigeko Kijimoto-Ochiai, Satoshi Uemura, Jin-ichi Inokuchi

Journal:

Biochemical and Biophysical Research Communications

Year:

2009

Language:

english

File:

PDF, 452 KB

english, 2009

35

Inhibition of sphingolipid induced apoptosis by caspase inhibitors indicates that sphingosine acts in an earlier part of the apoptotic pathway than ceramide

Elizabeth A Sweeney, Jin-ichi Inokuchi, Yasuyuki Igarashi

Journal:

Year:

1998

Language:

english

File:

PDF, 164 KB

english, 1998

36

In vitro assay system for synapse formation between cultured neurons of mice

Akihiro Mizutani, Jin-Ichi Inokuchi, Yoichiro Kuroda

Journal:

Neuroscience Research

Year:

1998

Language:

english

File:

PDF, 122 KB

english, 1998

37

Heterogeneity of gangliosides among T cell subsets

Inokuchi, Jin-ichi, Nagafuku, Masakazu, Ohno, Isao, Suzuki, Akemi

Journal:

Cellular and Molecular Life Sciences

Year:

2013

Language:

english

File:

PDF, 776 KB

english, 2013

38

Antihypertensive substance in seeds of Areca catechu L.

Jin-ichi Inokuchi, Hikaru Okabe, Tatsuo Yamauchi, Atsuo Nagamatsu, Gen-ichiro Nonaka, Itsuo Nishioka

Journal:

Year:

1986

Language:

english

File:

PDF, 368 KB

english, 1986

39

346 Effects of D-PDMP and GQ1B on synapse formation in cultured cortical neurons

Akihiro Mizutani, Yoichiro Kuroda, Kazuyo Muramoto, Kazuo Kobayashi, Kiwamu Yamagishi, Jin-Ichi Inokuchi

Journal:

Neuroscience Research

Year:

1997

Language:

english

File:

PDF, 97 KB

english, 1997

40

Expression machinery of GM4: the excess amounts of GM3/GM4S synthase (ST3GAL5) are necessary for GM4 synthesis in mammalian cells

Uemura, Satoshi, Go, Shinji, Shishido, Fumi, Inokuchi, Jin-ichi

Journal:

Glycoconjugate Journal

Year:

2014

Language:

english

File:

PDF, 459 KB

english, 2014

41

GM3 and diabetes

Inokuchi, Jin-ichi

Journal:

Glycoconjugate Journal

Year:

2014

Language:

english

File:

PDF, 346 KB

english, 2014

42

Functional mapping and implications of substrate specificity of the yeast high-affinity leucine permease Bap2

Usami, Yuki, Uemura, Satsohi, Mochizuki, Takahiro, Morita, Asami, Shishido, Fumi, Inokuchi, Jin-ichi, Abe, Fumiyoshi

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

2014

Language:

english

File:

PDF, 1.52 MB

english, 2014

43

Antitumor activity via inhibition of glycosphingolipid biosynthesis

Inokuchi, Jin-Ichi, Mason, Inez, Radin, Norman S.

Journal:

Year:

1987

Language:

english

File:

PDF, 607 KB

english, 1987

44

Tripeptidyl carboxypeptidase activity of kininase II (angiotensin-converting enzyme)

Inokuchi, Jin-Ichi, Nagamatsu, Atsuo

Journal:

Biochimica et Biophysica Acta (BBA) - Enzymology

Year:

1981

Language:

english

File:

PDF, 475 KB

english, 1981

45

Synthesis of glucosylceramide analogues: imino-linked 5a-carbaglycosylceramides, potent and specific glucocerebrosidase inhibitors

Ogawa, Seiichiro, Tsunoda, Hidetoshi, Inokuchi, Jin-ichi

Journal:

Journal of the Chemical Society Chemical Communications

Year:

1994

Language:

english

File:

PDF, 221 KB

english, 1994

46

Distinct selectivity of gangliosides required for CD4+ T and CD8+ T cell activation

Inokuchi, Jin-ichi, Nagafuku, Masakazu, Ohno, Isao, Suzuki, Akemi

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Year:

2015

Language:

english

File:

PDF, 1.68 MB

english, 2015

47

Effect of Honeycomb-Patterned Surface Topography on the Function of Mesenteric Adipocytes

Sato, Takashige, Tanaka, Masaru, Yamamoto, Sadaaki, Ito, Emiko, Shimizu, Kyoko, Igarashi, Yasuyuki, Shimomura, Masatsugu, Inokuchi, Jin-ichi

Journal:

Journal of Biomaterials Science Polymer Edition

Year:

2010

Language:

english

File:

PDF, 1.84 MB

english, 2010

48

The regulation of ER export and Golgi retention of ST3Gal5 (GM3/GM4 synthase) and B4GalNAcT1 (GM2/GD2/GA2 synthase) by arginine/lysine-based motif adjacent to the transmembrane domain

Uemura, Satoshi, Shishido, Fumi, Kashimura, Madoka, Inokuchi, Jin-ichi

Journal:

Year:

2015

Language:

english

File:

PDF, 5.20 MB

english, 2015

49

Tripeptidyl carboxypeptidase activity of angiotensin I-converting enzyme in human tissues and fluids

SCHARPE, SIMON, HENDRIKS, DIRK, INOKUCHI, JIN-ICHI, VAN SANDE, MARC

Journal:

Biochemical Society Transactions

Year:

1986

Language:

english

File:

PDF, 219 KB

english, 1986

50

Gaucher's disease: increase of di- and tri-peptidyl carboxypeptidase in plasma

VAN SANDE, MARC, SCHARPE, SIMON, VAN HOOF, FRANCOIS, DE BARSY, THIERRY, INOKUCHI, JIN-ICHI, HENDRIKS, DIRK

Journal:

Biochemical Society Transactions

Year:

1987

Language:

english

File:

PDF, 219 KB

english, 1987

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